In the present report, the International Independent Expert Mechanism to Advance Racial Justice and Equality in Law Enforcement examines how racism is embedded in drug control systems and shapes their impacts on Africans and people of African descent. It begins by exploring the root causes of racial discrimination in drug policy, including the legacies of colonialism, the racialization of drugs, the influence of militarized approaches and the “war on drugs”. The Mechanism then analyses manifestations of racial discrimination across the criminal justice system. Building on this analysis, it examines the intersection of drug policy with other grounds of discrimination, such as gender, highlighting how intersecting forms of discrimination can increase the risk of human rights violations. The Mechanism also identifies factors that exacerbate these harms and concludes by highlighting promising practices and policy approaches aimed at addressing racial discrimination and advancing more equitable and rights-based drug policies. The present report also includes information on the activities of the Mechanism since its previous report.